Frequency: Quarterly E- ISSN: 2250-026X P- ISSN: 2249-3557 IBI Factor: 4.09, Global Impact Factor 0.76 Abstracted/ Indexed in: Ulrich's International Periodical Directory, Google Scholar, SCIRUS, Genamics Journal Seek, PSOAR, getCITED, InfoBase Index, EBSCO Information Services
Quarterly published in print and online "Inventi Impact: Planta Activa" publishes high quality unpublished as well as high impact pre-published research and reviews catering to the needs of researchers and professionals. This journal focuses on pharmaceutically active constituents of the plant origin. The specific areas included are extraction and isolation, chemoprofiling and bioprofiling, and formulation and regulatory aspects of active botanicals.
The leaves of Morus alba L. are an important herbal medicine in Asia. The systematic\nisolation of the metabolites of the leaves of Morus alba L. was achieved using a combination of\nliquid chromatography techniques. The structures were elucidated by spectroscopic data analysis\nand the absolute configuration was determined based on electronic circular dichroism (ECD)\nspectroscopic data and hydrolysis experiments. Their biological activity was evaluated using different\nbiological assays, such as the assessment of their capacity to inhibit the aldose reductase enzyme;\nthe determination of their cytotoxic activity and the evaluation of their neuroprotective effects against\nthe deprivation of serum or against the presence of nicouline. Chemical investigation of the leaves\nof Morus alba L. resulted in four new structures 1ââ?¬â??4 and a known molecule 5. Compounds 2 and\n5 inhibited aldose reductase with IC50 values of 4.33 Ã?¼M and 6.0 Ã?¼M compared with the potent\nAR inhibitor epalrestat (IC50 1.88 Ã?â?? 10âË?â??3 Ã?¼M). Pretreatment with compound 3 decreased PC12 cell\napoptosis subsequent serum deprivation condition and pretreatment with compound 5 decreased\nnicouline-induced PC12 cell apoptosis as compared with control cells (p < 0.001)....
To evaluate the fluctuation of secondary metabolites in Arabian lilac during a year, aerial\nparts of the plant were harvested in the middle of each month. The essential oils content from fresh\nand dried plant materials was analyzed by gas chromatography-flame ionization detector (GC-FID)\nand gas chromatography-mass spectrometer (GC-MS), individually. Phytochemical contents, along\nwith antiradical scavenging potential of the related methanol extracts were separately assessed.\nThe spring and autumn samples (fresh and dried) yielded more essential oil than the other samples.\nForty-one compounds were identified totally in the oils and the major constituents characterized\nwere......................
The leaves of mulberry, Azolla spp., sunflower sprouts, cashew nut, and mung bean are considered rich sources of plant protein with high levels of branched-chain amino acids. Furthermore, they contain beneficial phytochemicals such as antioxidants and anti-inflammatory agents. Additionally, there are reports suggesting that an adequate consumption of amino acids can reduce nerve cell damage, delay the onset of memory impairment, and improve sleep quality. In this study, protein isolates were prepared from the leaves of mulberry, Azolla spp., sunflower sprouts, cashew nut, and mung bean. The amino acid profile, dietary fiber content, phenolic content, and flavonoid content were evaluated. Pharmacological properties, such as antioxidant, anticholinesterase, monoamine oxidase, and γ-aminobutyric acid transaminase (GABA-T) activities, were also assessed. This study found that concentrated protein from mung beans has a higher quantity of essential amino acids (52,161 mg/100 g protein) compared to concentrated protein from sunflower sprouts (47,386 mg/100 g protein), Azolla spp. (42,097 mg/100 g protein), cashew nut (26,710 mg/100 g protein), and mulberry leaves (8931 mg/100 g protein). The dietary fiber content ranged from 0.90% to 3.24%, while the phenolic content and flavonoid content ranged from 0.25 to 2.29 mg/g and 0.01 to 2.01 mg/g of sample, respectively. Sunflower sprout protein isolates exhibited the highest levels of dietary fiber (3.24%), phenolic content (2.292 ± 0.082 mg of GAE/g), and flavonoids (2.014 mg quercetin/g of sample). The biological efficacy evaluation found that concentrated protein extract from sunflower sprouts has the highest antioxidant activity; the percentages of inhibition of 1,1- diphenyl-2-picrylhydrazyl radical (DPPH) and 2,2-azino-bis-(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) radical were 20.503 ± 0.288% and 18.496 ± 0.105%, respectively. Five plant-based proteins exhibited a potent inhibition of acetylcholinesterase (AChE) enzyme activity, monoamine oxidase (MAO) inhibition, and GABA-T ranging from 3.42% to 24.62%, 6.14% to 20.16%, and 2.03% to 21.99%, respectively. These findings suggest that these plant protein extracts can be used as natural resources for developing food supplements with neuroprotective activity....
This article aims to provide detailed information on Malaysian plants used for treating inflammation. An extensive search on\nelectronic databases including PubMed, Google Scholar, Scopus, and ScienceDirect and conference papers was done to find\nrelevant articles on anti-inflammatory activity of Malaysian medicinal plants. The keyword search terms used were â??inflammation,â?\nâ??Malaysia,â? â??medicinal plants,â? â??mechanisms,â? â??in vitro,â? and â??in vivo.â? As a result, 96 articles on anti-inflammatory\nactivity of Malaysian medicinal plants were found and further reviewed. Forty-six (46) plants (in vitro) and 30 plants (in vivo) have\nbeen identified to possess anti-inflammatory activity where two plants, Melicope ptelefolia (Tenggek burung) and Portulaca\noleracea (Gelang pasir), were reported to have the strongest anti-inflammatory activity of more than 90% at a concentration of\n250 ... It was showed that the activity was mainly due to the occurrence of diverse naturally occurring phytochemicals from\ndiverse groups such as flavonoids, coumarins, alkaloids, steroids, benzophenone, triterpenoids, curcuminoids, and cinnamic acid.\nHence, this current review is a detailed discussion on the potential of Malaysian medicinal plants as an anti-inflammatory agent\nfrom the previous studies. However, further investigation on the possible underlying mechanisms and isolation of active\ncompounds still remains to be investigated....
Depression is a mood disorder; it has been treated and classified in a number of ways. Herbal preparations used by many people for the treatment of depression and a search for novel anti-depressant plants has been progressed significantly in the past few decades. The potential of the herbal remedies has been evaluated by using various animal models. This review deals with the various herbal extracts and their chemical constituents that are beneficial in the treatment of depression. Herbal plants have shown the anti-depressant effect by virtue of the combined effect of their chemical constituents. A large number of synthetic anti-depressant drugs have been used to treat the depression in the clinically depressed patients but they have the side effects. So, to overcome these effects we have a need of herbal anti-depressants. Herbal remedies that have demonstrable psychotherapeutic activities have provided a potential to treat depression and deserve increased attention in future studies. The present review deals with the herbal plants and the plant based preparation having anti-depressant potential in the animal models and are used clinically. These studies have provided useful information for the development of new pharmacotherapies from herbal plants for use in clinical psychiatry....
Banana (Musa spp.) is one of the world’s most important crops cultivated in tropical and subtropical areas of the globe. Banana is a major source of macro-elements, especially potassium and contains health-good ingredients such as resistant starch, total dietary fibers, rapidly digestible starch and slowly digestible starch. Oligosaccharides present in bananas that have found application in the prevention of muscular contractions, regulation of blood pressure, prevention of Colon cancer and diabetes and in the cure of intestinal disorders when unripe....
An endangered species is a population of organisms/ plants which is at risk of becoming extinct because it is either few in numbers, or threatened by changing environmental or predation parameters. WHO has listed over 21,000 plant species used for medicinal purposes across the world. India, having an array of topographic and climatic variations, harbour flora of greater diversity and an estimated 1,20,000 plant species, out of 4,00,000 known species of this planet inhabit Indian sub-continent. The primary factors contributing to extinction are habitat loss, introduced species, over exploitation and population. Deforestation processes practiced for agriculture or for construction of dams or for residential purposes cause soil erosion, which leads to leeching of some valuable nutrients needed for growth of medicinal plants and cause vanishing of important flora and fauna from the ecosystems which is an irreversible damage to the nature. Over harvesting and over exploitation is another factor, which has greatly threatened the existence of medicinal plants. Today, species become endangered primarily because of human activities. Their lists include about 34,000 species of plants that are threatened or endangered. Conservation of the threatened medicinal taxa is clearly one of the properties towards which available technologies must be directed, cultivation is one way to prevent the genetic erosion of medicinal plants in India....
Acne vulgaris (commonly called acne) is a common skin condition, caused by changes in the pilosebaceous units, skin structures consisting of a hair follicle and its associated sebaceous gland via androgen stimulation. Acne mainly affects the teenagers up to 95% boys and 83% girls due to the hormonal changes. The incidence of severity of acne peak at 40% in 14-17 year old girls and 35% in boys aged 16-19. Acne treatment involves the correcting of the altered pattern of follicular keratinization, decreasing sebaceous gland activity, decreasing Propionibacterium acnes population and producing anti-inflammatory effect. Tetracycline, erythromycin, roxithromycin, clindamycin, benzoyl peroxide and azelaic acid are generally employed to inhibit inflammation or to kill the bacteria. Long term use of these antibiotics cause significant antibiotic resistance and multiple drug resistance in acne patients. There are various treatments available in the market like, hormonal therapy, oral therapy, phototherapy, laser treatment. Other alternative treatment is laser therapy, cosmetic surgery, etc. Which is a costlier option. In order to overcome the problem of antibiotic resistance, medicinal plants have been extensively studied as an alternative treatment for acne. In addition, the medicinal plants/ naturally derived compounds are believed to be safer than synthetic compounds....
Medicinal plants have played a key role in world health and promising future. Garcinia indica, a small to moderate size plant belonging to the Clusiaceae family or Guttiferae, according to the old classification, has approximately 1350 species.It has a number of benefits which can be a boon for patients suffering from various ailments.In Ayurveda, Kokum traditionally used for edema, rheumatism, delayed menstruation, constipation, bowel complaints, intestinal parasites, skin rashes and burns. Kokum fruit possess useful antioxidant, chelating, anti-cancer,anti-fungal, anti-inflammatory, anti-bacterial, cardio protective and anti-ulcer activities. The peel of this fruit contains the highest proportion of xanthones which can be beneficial for the body as a whole....
Cucurbita pepo (C. pepo) is a perennial creeping herb belonging to the family Cucurbitaceae. The seeds of which contain sizable amounts of protein (35%) and approximately 50% fatty oil, whose fatty acid profile is dominated by unsaturated fatty acids, namely Linoleic and oleic acid. There are many trace constituents like tocopherols (0.1%) and phytosterols (total 0.1 to 0.5%). A wide range of chemical compounds including sterols, Triterpenoids, tocopherols, and fatty acids have been isolated from the species. Its extracts have been found to possess various pharmacological activities. Below, we give a comprehensive review of its ethnomedical uses, chemical constituents, and pharmacological profile as a medicinal plant. Particular attention is given to its, anti-inflammatory, antidiabetic, antidepressant, antioxidant, diuretic, hepatoprotective, antiparasitic and anthelmintic, effects so that its potential uses in pharmaceutics can be better evaluated....
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